Sponsored
Enfamil Optimum Enspire Ready to Feed Infant Formula - 32 fl oz
$15.99 ($0.50/fluid ounce)
In Stock
Eligible for registries and wish lists
At a glance
Sponsored
About this item
Highlights
- NEW LOOK, SAME PREMIUM NUTRITION: Previously known as Enspire Optimum, Enfamil Optimum Baby Formula now has a refreshed look and name while offering the same trusted infant nutrition parents rely on.
- OUR CLOSEST FORMULA TO BREAST MILK: Enfamil Optimum Ready-to-Feed includes two of the most abundant human milk oligosaccharides (HMOs)—2’-FL and LnNT.
- SUPPORTS IMMUNE & BRAIN DEVELOPMENT: This ready-to-feed formula provides brain-building DHA and dual HMOs (2’-FL & LnNT) to nourish both cognitive and immune development in your growing baby.
- TRUSTED NUTRITION FOR COMBO FEEDING: With key nutrients for growing babies, Enfamil Optimum gives parents the flexibility to supplement breastfeeding with our closest formula to breast milk.
- NO MIXING, READY-TO-FEED: Enfamil Optimum ready-to-feed offers complete infant nutrition in a convenient, no-prep format—ideal for supplementing breast milk or feeding late at night, while traveling, and or on-the-go!
- NO ARTIFICIAL ADDITIVES & NON-GMO: Has clinically-tested, non-GMO ingredients. Free from artificial growth hormones, colors, and flavors. Enfamil Optimum does not contain high fructose corn syrup and is made with milk sourced from the United States. Optimum is premium baby formula for infants through 12 months of age.
- PEDIATRICIAN & PARENT TRUSTED: Enfamil is the #1 trusted infant formula brand by pediatricians* and parents of those who have a preference.
- JOIN ENFAMIL FAMILY BEGINNINGS® & EARN REWARDS: Sign up for Enfamil Family Beginnings® to enjoy exclusive savings, expert tips, and personalized support—plus earn rewards with every eligible purchase.
- CHOOSE A CASE PACK FOR ADDED CONVENIENCE: Stock up with a case pack of Enfamil formula to help ensure you’re always prepared—ideal for regular feedings and busy routines.
Description
Give your baby the best start with Enfamil Optimum Ready-to-Feed—our most advanced formula designed to support immune health and brain development, inspired by the composition of breast milk.
Enfamil Optimum includes a dual prebiotic blend—2'-FL and LnNT—two of the most abundant human milk oligosaccharides (HMOs) naturally found in breast milk, to help nourish your baby’s developing immune system. It also contains brain-building DHA to support early cognitive development.
Made without artificial growth hormones*, artificial colors, or flavors, Enfamil Optimum is a non-GMO† formula offering premium nutrition through 12 months of age.
Whether you're combo feeding or transitioning from breastfeeding, this ready-to-feed format offers both peace of mind and on-the-go convenience—no mixing or prep required.
Join Enfamil Family Beginnings® to earn rewards with every purchase and access exclusive benefits and support. Details: https://www.enfamil.com/baby-formula-coupons-samples/
SNAP eligible.
Enfamil Optimum includes a dual prebiotic blend—2'-FL and LnNT—two of the most abundant human milk oligosaccharides (HMOs) naturally found in breast milk, to help nourish your baby’s developing immune system. It also contains brain-building DHA to support early cognitive development.
Made without artificial growth hormones*, artificial colors, or flavors, Enfamil Optimum is a non-GMO† formula offering premium nutrition through 12 months of age.
Whether you're combo feeding or transitioning from breastfeeding, this ready-to-feed format offers both peace of mind and on-the-go convenience—no mixing or prep required.
Join Enfamil Family Beginnings® to earn rewards with every purchase and access exclusive benefits and support. Details: https://www.enfamil.com/baby-formula-coupons-samples/
SNAP eligible.
Serving Size: 5 fl oz
Amount :
Calories: 100
% Daily Value*
Protein 2.1g
Total Fat 5.3g
Total Carbohydrate 11.1g
Water 133g
Omega-6 (linoleic acid LA) 780mg
Vitamin A 300IU
Vitamin D 70IU
Vitamin E 2IU
Vitamin K 9mcg
Thiamin 80mcg
Riboflavin 140mcg
Vitamin B6 60mcg
Vitamin B12 0.3mcg
Niacin 1000mcg
Folic Acid 16mcg
Pantothenic Acid 500mcg
Biotin 3mcg
Vitamin C 12mg
Choline 24mg
Inositol 24mg
Calcium 78mg
Phosphorus 43mg
Magnesium 8mg
Iron 1.8mg
Zinc 1mg
Manganese 15mcg
Copper 75mcg
Iodine 15mcg
Selenium 2.8mcg
Sodium 27mg
Potassium 108mg
Chloride 63mg
* Percentage of Daily Values are based on a 2,000 calorie diet.
Ingredients:
water, nonfat milk, lactose, vegetable oil (contains one or more of the following: palm olein oil, coconut oil, soy oil, high oleic sunflower oil), and less than 2%: lacto-n-neotetraose#, 2'-fucosyllactose#, whey protein concentrate**, mortierella alpina oil††, schizochytrium sp. oil‡‡, potassium citrate, calcium carbonate, calcium chloride, magnesium phosphate, sodium chloride, calcium phosphate, ferrous sulfate, zinc sulfate, cupric sulfate, manganese sulfate, sodium selenite, potassium iodide, mono- and diglycerides, soy lecithin, ascorbic acid, sodium ascorbate, vitamin e acetate, niacinamide, calcium pantothenate, vitamin a palmitate, thiamin hydrochloride, riboflavin, vitamin b6 hydrochloride, folic acid, vitamin k1, biotin, vitamin b12, carrageenan, choline chloride, inositol, vitamin d3, taurine, l-carnitine. #a source of hmo (2'-fl & lnnt human milk oligosaccharides) **a source of mfgm (milk fat globule membrane composed of proteins and fats) components ††a source of arachidonic acid (ara) ‡‡a source of docosahexaenoic acid (dha)' '
Allergens & Warnings:
DO NOT USE IF PROTECTIVE SEAL AROUND CAP, OR IF FOIL SEAL UNDER CAP, IS DAMAGED OR MISSING., WARNING: Do not use a microwave oven to warm formula. Serious burns may result.Baby Formula Focus: Brain Development, Immune System Support, Growth Support
Base Ingredient: Milk
Dietary Needs: Naturally Flavored
Features: No Artificial Colors
Form: Liquid
State of Readiness: Ready to Use
Package Quantity: 1
Age Stage: Infant
Net weight: 32 fl oz (US)
TCIN: 94051720
UPC: 300875135464
Item Number (DPCI): 007-09-0091
Origin: Made in the USA
Grocery Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers. Any additional pictures are suggested servings only.
If the item details aren’t accurate or complete, we want to know about it.
Shipping details
Estimated ship dimensions: 3.2 inches length x 3.5 inches width x 9.57 inches height
Estimated ship weight: 2.33 pounds
Return details
This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup. If purchased online with SNAP EBT, this item must be returned within 90 days of the date it was shipped, delivered by a Shipt shopper, or made ready for pickup. This 90-day return window is required by SNAP.
See the return policy for complete information.
Q: Is the liquid version more potent than the powder? For some reasons my baby prefers the liquid premade ones. Also the liquid ones look darker than the powder version. Am I wrong?
submitted by Baby boy - 6 months ago
A: Hello Baby boy! Thank you for choosing Enfamil Optimum! We are sorry you had that experience and would like to get a little more information from you. Please give us a call at 1-800-222-9123, choose option 1, and reference #6906162. Thanks! Bev, Enfamil Expert
submitted byEnfamil Team - 6 months agoBrand expert
Q: Do you have to store this In the fridge after opening?
submitted by Lacy - 8 months ago
A: Hello, Lacy! Our opened or prepared liquid infant formulas can be kept covered in the refrigerator for up to 48 hours. -Katelin, Enfamil Expert
submitted byEnfamil Team - 8 months agoBrand expert
Q: Since this is missing the lactoferrin, what would be the difference with this and nueropro?
submitted by Ash - 9 months ago
A: Hello, Ash! Enfamil Optimum has naturally occurring MFGM (Milk Fat Globule Membrane) components and well as LnNT (Lacto-N-tetraose) HMO, components also found in breast milk. Enfamil NeuroPro Infant has naturally occurring MFGM components, however, it does not contain LnNT (Lacto-N-tetraose) HMO. LnNt primarily functions as a prebiotic, meaning it selectively nourishes beneficial bacteria in the infant's gut, promoting healthy gut development and potentially supports immune function. -Katelin, Enfamil Expert
submitted byEnfamil Team - 9 months agoBrand expert
Frequently bought together
Highly rated
$9.99($0.83/fluid ounce)
Buy 1, get 1 30% off select Enfamil neuropro
4.8 out of 5 stars with 8467 ratings
Highly rated
$17.99($0.37/fluid ounce)
Buy 1, get 1 30% off select Enfamil neuropro
4.7 out of 5 stars with 8324 ratings
Highly rated
$11.89($0.37/fluid ounce)
Buy 1, get 1 30% off select Enfamil neuropro
4.7 out of 5 stars with 8619 ratings
Discover more options
Highly rated
$11.89($0.37/fluid ounce)
Buy 1, get 1 30% off select Enfamil neuropro
4.7 out of 5 stars with 8619 ratings
$12.89($0.40/fluid ounce)
4.7 out of 5 stars with 7409 ratings
Related Categories
Guests are saying
This formula is highly praised by guests for its close resemblance to breast milk, making it an excellent choice for supplementing or transitioning from breastfeeding. Many guests appreciate its easy digestibility and the nutritional benefits it offers, including essential components like lactoferrin. The convenience of ready-to-use options is also highlighted, making it a practical choice for busy parents. Overall, it has been a reliable solution for many families seeking quality nutrition for their infants.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.8 out of 5 stars with 3412 reviews
easy on tummy: 5 out of 5
easy to prepare: 5 out of 5
quality: 5 out of 5
value: 5 out of 5
100% would recommend
2 recommendations
5 out of 5 stars
20 December, 2025
originally posted on Enfamil
The only formula my breastfed baby would take.
[This review was collected as part of a promotion.] We tried a few different formulas that were labeled “close to breastmilk” but he wouldn’t take any until we tried Enfamil Optimum. Now I am able to have my baby take formula on the moments I may not be around.
1 reply from Customer Care team - 14 days ago
We work hard to bring you the very best products. Thanks for leaving us a review, Mommajx! — Tasha, Enfamil Expert
5 out of 5 stars
19 December, 2025
originally posted on Enfamil
Optimum is great my daughter loves it
I switched to this brand from great reviews I heard from family members. My daughter does not use any problems with it and the formula itself has a plethora of good vitamins and nutrients. It’s the perfect supplement for my child when not breast-feeding.
1 reply from Customer Care team - 17 days ago
We are so happy you chose us to supplement feedings for your little one, Courtland! Thank you for being part of our Enfamil family. — Tasha, Enfamil Expert
5 out of 5 stars
18 December, 2025
originally posted on Enfamil
I like it
[This review was collected as part of a promotion.] Just recently bought it to dual feed when i go back to work and my baby looks like there enjoying there bottles.Less spit up an less gassy.
1 reply from Enfamil Costumer Care team - 16 days ago
Hello Cherryberry! We would love to speak with you directly about your experience with our Enfamil Enspire pwd! One of our team members will be reaching out to you via email, but if you would like to speak with us immediately, please give us a call at 1-800-222-9123, select option 1 and reference #7708749. We look forward to speaking with you and seeing how we can help! -Hazel, Enfamil Expert
5 out of 5 stars
18 December, 2025
originally posted on Enfamil
Great choice
[This review was collected as part of a promotion.] Sometimes we get this one as a step up from the purple regular enfamil but a price cost below the purple optimum. I feel like the formula is softer and the powder is better and mixes well
1 reply from Enfamil Customer Care team - 16 days ago
Hello! We are glad to hear that you have been enjoying using our Enfamil® Optimum™! If you have any further questions, please give us a call at 1-800-222-9123, choose option 1, and reference #7708937. Thanks! - Enzo , Enfamil Expert
5 out of 5 stars
17 December, 2025
originally posted on Enfamil
ONE OF MY FAVORITES
[This review was collected as part of a promotion.] this formal is amazing switching between bf and formal feeding we have no spit up at all
1 reply from Customer Care team - 19 days ago
We work hard to bring you the very best products. Thanks for leaving us a review, Kadi! — Tasha, Enfamil Expert
5 out of 5 stars
15 December, 2025
originally posted on influenster.com
Gentle on the stomach, easy to mix, minimal spit-u
We’ve been using Enfamil Optimum Infant for our baby and it’s been working really well for us. One of the first things we noticed was how comfortable our baby seemed after feedings. Spit-up has been minimal compared to the formula we tried before, which was a big relief. We also haven’t had any issues with skin irritation or rashes, which was something we were watching closely. It seems gentle and easy on our baby’s stomach. The formula mixes smoothly and has a nice consistency — no clumps or foam — which makes bottle prep quick, especially during late-night feeds. Overall, our baby has been growing well and meeting developmental milestones, and we feel good knowing this formula supports brain development too. We’re happy with it and would definitely recommend it to other parents looking for a reliable, gentle formula.
1 reply from Enfamil Costumer Care team - 20 days ago
Hello! We would love to speak with you directly about your experience with our Enfamil® Optimum™ (Enspire)! One of our team members will be reaching out to you via email, but if you would like to speak with us immediately, please give us a call at 1-800-222-9123, select option 1 and reference #7686660. We look forward to speaking with you and seeing how we can help! -Hazel, Enfamil Expert
5 out of 5 stars
15 December, 2025
originally posted on Enfamil
this is really good for everyone has baby
[This review was collected as part of a promotion.] i got this for wonder box and i'm excited to used it
1 reply from Customer Care team - 21 days ago
What a great review, Chelsea! Thanks! — Marcy, Enfamil Expert
5 out of 5 stars
14 December, 2025
originally posted on Enfamil
Incredible formula!
I used this with both of my children. With my 9 month old currently and the purple one with my 6 year old back when it was still ENSPIRE. it worked very well with them and they both are sharp as a tack for their age and reached milestones earlier than the average baby. I think it has a lot to do with the ingredient found in breast milk which I’m so thankful for since I wasn’t able to breastfeed for very long
1 reply from Customer Care team - 21 days ago
We appreciate you using Enfamil with each of your babies and are happy that you continue to be a part of the Enfamil family! — Marcy, Enfamil Expert
5 out of 5 stars
12 December, 2025
originally posted on Enfamil
Closest thing to breast milk
[This review was collected as part of a promotion.] I used this in unison with breast feeding and my baby could hardly tell the difference. I had a hard time producing the amount of breast milk that I wanted to produce and wanted to make sure that my baby still got all the nutrients he deserved and this formula came in clutch.
1 reply from Customer Care team - 24 days ago
We work hard to bring you the very best products. Thanks for leaving us a review! — Tasha, Enfamil Expert
5 out of 5 stars
12 December, 2025
originally posted on Enfamil
Tried 3 different and this is the one
My baby tolerates this formulas the best as a breastfed baby we formula feed on the weekends while I’m at work
1 reply from Customer Care team - 24 days ago
Thank you for telling us about your experience, Lila. We are grateful for such a wonderful review! — Marcy, Enfamil Expert
4 out of 5 stars
10 December, 2025
originally posted on Enfamil
Great source of nutrients
My baby has been using Enfamil formula since she turned 2 months and it has been great! No complications and she is big and healthy.
1 reply from Customer Care team - 25 days ago
We appreciate your feedback regarding our product, MelyN! Thank you for choosing Enfamil to help give your little girl the best start in life! — Tasha, Enfamil Expert
5 out of 5 stars
9 December, 2025
originally posted on Enfamil
Great milk
I bought this product few months ago and is super great
1 reply from Customer Care team - 26 days ago
What a great review, Daughter! Thanks! — Marcy, Enfamil Expert
5 out of 5 stars
9 December, 2025
originally posted on Enfamil
My favorite
This is my absolute favorite formula wish it wasn't so much but it's worth it
1 reply from Customer Care team - 27 days ago
Thank you for sharing your experience using our product, NLynn90! We appreciate your feedback! — Marcy, Enfamil Expert
5 out of 5 stars
9 December, 2025
originally posted on Enfamil
Great formula for supplementing
I bought this product for my daughter for supplementing due to my low milk supply. This formula has been so gentle on my daughter's stomach.
1 reply from Customer Care team - 26 days ago
We are so happy you chose us to help you supplement feedings for your little girl, MommaOf3! Thank you for being part of our Enfamil family. — Abby, Enfamil Expert
5 out of 5 stars
9 December, 2025
originally posted on Enfamil
No tummy issues
[This review was collected as part of a promotion.] We started my daughter (2mo) on this about a week after she was born. I breastfed/supplemented with donor milk while in the hospital. She has not had any digestive issues with this formula. Plenty of bowl movements and no serious gas.
1 reply from Enfamil Customer Care team - 27 days ago
Hello Kaitlin! We would love to speak with you directly about your experience with our Enfamil Enspire Optimum! One of our team members will be reaching out to you via email, but if you would like to speak with us immediately, please give us a call at 1-800-222-9123, select option 1 and reference #7653969. We look forward to speaking with you and seeing how we can help! - Jude, Enfamil Expert
5 out of 5 stars
8 December, 2025
originally posted on Enfamil
Love!
[This review was collected as part of a promotion.] Have never had any issues! Makes me feel good feeding it to my baby being close to breast milk.
1 reply from Customer Care team - 28 days ago
We appreciate your feedback regarding our product, Slp816! Thank you for choosing Enfamil to help give your little one the best start in life! — Tasha, Enfamil Expert
5 out of 5 stars
7 December, 2025
originally posted on Enfamil
Not yellow with an over powering smell
Love this for my past 3 babies and is going to be my choice for my 4th
1 reply from Customer Care team - 28 days ago
We appreciate you using Enfamil with each of your babies and are happy that you continue to be a part of the Enfamil family, Elizabeth! — Abby, Enfamil Expert
5 out of 5 stars
6 December, 2025
originally posted on Enfamil
Support immune system
[This review was collected as part of a promotion.] My bay started this fomula from second week. Easy to switch.
1 reply from Customer Care team - 28 days ago
Thank you for being part of the Enfamil family, Sonia. — Tasha, Enfamil Expert
5 out of 5 stars
6 December, 2025
originally posted on Enfamil
The best formula
This is the best formula to pick for your baby. It’s worth it!
1 reply from Customer Care team - 28 days ago
Thanks for such a great review, Sarah! — Tasha, Enfamil Expert
5 out of 5 stars
4 December, 2025
originally posted on Enfamil
Great Formula! Works well for my baby
[This review was collected as part of a promotion.] I bought this formula a couple of months ago when I had to start supplementing my breastfed baby. He was doing well on it. A couple weeks ago I made the decision to stop our breastfeeding journey due to low supply and he is loving Enfamil Optimum and doing very well on it. I highly recommend this to any mom looking for a formula to switch their breastfed baby to or any mom looking for formula!
1 reply from Customer Care team - 1 month ago
Thank you for telling us about your experience, lex1998. We are grateful for such a wonderful review! — Marcy, Enfamil Expert