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Enfamil Optimum Enspire Powder Infant Formula - 30oz
$54.99 ($1.83/ounce)
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About this item
Highlights
- NEW LOOK, SAME PREMIUM NUTRITION: Previously known as Enspire Optimum, Enfamil Optimum Baby Formula now has a refreshed look and name while offering the same trusted infant nutrition parents rely on.
- OUR CLOSEST FORMULA TO BREAST MILK: Enfamil Optimum is the first and only leading baby formula to include lactoferrin, a key immune-supporting protein found in colostrum and breastmilk.
- SUPPORTS IMMUNE & BRAIN DEVELOPMENT: This premium formula includes lactoferrin, a dual prebiotic blend (2'FL & LnNT), and brain-building DHA—all clinically-tested ingredients.
- COMPLETE NUTRITION FOR DAILY FEEDINGS: A great choice for everyday formula use, this 30 oz tub of Enfamil Optimum provides complete nutrition in a convenient powder format—perfect for full-time feeding or supplementing breast milk.
- TRUSTED NUTRITION FOR COMBO FEEDING: With key nutrients for growing babies, Enfamil Optimum gives parents the flexibility to supplement breastfeeding with our closest formula to breast milk.
- NO ARTIFICIAL ADDITIVES & NON-GMO: Has clinically-tested, non-GMO ingredients. Free from artificial growth hormones, colors, and flavors. Enfamil Optimum does not contain high fructose corn syrup and is made with milk sourced from the United States. Optimum is premium baby formula for infants through 12 months of age.
- PEDIATRICIAN & PARENT TRUSTED: Enfamil is the #1 trusted infant formula brand by pediatricians* and parents, making Optimum baby formula a reliable choice for growing families.
- JOIN ENFAMIL FAMILY BEGINNINGS® & EARN REWARDS: Sign up for Enfamil Family Beginnings® to enjoy exclusive savings, expert tips, and personalized support—plus earn rewards with every eligible purchase.
- CHOOSE A CASE PACK FOR ADDED CONVENIENCE: Stock up with a case pack of Enfamil formula to help ensure you’re always prepared—ideal for regular feedings and busy routines.
Description
Give your baby a great start with Enfamil Optimum—our most advanced formula designed to support immune health and brain development, inspired by the composition of breast milk.
Enfamil Optimum, formerly known as Enfamil Enspire Optimum, is our closest baby formula to breast milk. It has lactoferrin, a key immune-supporting protein also found in colostrum and breast milk. It also has a dual HMO blend—2'-FL and LnNT—two of the most abundant human milk oligosaccharides (HMOs) naturally found in breast milk, to help nourish your baby’s immune system.
It has brain-building DHA and is made without artificial growth hormones*, artificial colors, or flavors, Enfamil Optimum is a non-GMO† option for parents seeking premium infant nutrition through 12 months of age.
Whether you're combo feeding or transitioning from breastfeeding, this formula offers both peace of mind and convenience for growing families.
Join Enfamil Family Beginnings® to earn rewards with every purchase and access exclusive benefits and support. Details: https://www.enfamil.com/baby-formula-coupons-samples/
SNAP eligible.
Enfamil Optimum, formerly known as Enfamil Enspire Optimum, is our closest baby formula to breast milk. It has lactoferrin, a key immune-supporting protein also found in colostrum and breast milk. It also has a dual HMO blend—2'-FL and LnNT—two of the most abundant human milk oligosaccharides (HMOs) naturally found in breast milk, to help nourish your baby’s immune system.
It has brain-building DHA and is made without artificial growth hormones*, artificial colors, or flavors, Enfamil Optimum is a non-GMO† option for parents seeking premium infant nutrition through 12 months of age.
Whether you're combo feeding or transitioning from breastfeeding, this formula offers both peace of mind and convenience for growing families.
Join Enfamil Family Beginnings® to earn rewards with every purchase and access exclusive benefits and support. Details: https://www.enfamil.com/baby-formula-coupons-samples/
SNAP eligible.
Serving Size: 5 fl oz
Amount :
% Daily Value*
Protein 2.1g
Total Fat 5.3g
Total Carbohydrate 11.1g
Water 133g
Omega-6 (linoleic acid LA) 780mg
Vitamin A 300IU
Vitamin D 70IU
Vitamin E 2IU
Vitamin K 9mcg
Thiamin 80mcg
Riboflavin 140mcg
Vitamin B6 60mcg
Vitamin B12 0.3mcg
Niacin 1000mcg
Folic Acid 16mcg
Pantothenic Acid 500mcg
Biotin 3mcg
Vitamin C 12mg
Choline 24mg
Inositol 24mg
Calcium 78mg
Phosphorus 43mg
Magnesium 8mg
Iron 1.8mg
Zinc 1mg
Manganese 15mcg
Copper 75mcg
Iodine 15mcg
Selenium 2.8mcg
Sodium 27mg
Potassium 108mg
Chloride 63mg
* Percentage of Daily Values are based on a 2,000 calorie diet.
Ingredients:
nonfat milk, lactose, vegetable oil (contains one or more of the following: palm olein oil, coconut oil, soy oil, high oleic sunflower oil), whey protein concentrate++, and less than 2%: lacto-n-neotetraose~, 2'-fucosyllactose~, lactoferrin, mortierella alpina oil#, schizochytrium sp. oil**, calcium carbonate, calcium phosphate, cupric sulfate, ferrous sulfate, magnesium oxide, manganese sulfate, potassium chloride, potassium citrate, potassium iodide, sodium chloride, sodium selenite, zinc sulfate, soy lecithin, choline chloride, inositol, ascorbic acid, biotin, calcium pantothenate, folic acid, niacinamide, riboflavin, thiamin hydrochloride, vitamin b12, vitamin b6 hydrochloride, vitamin d3, vitamin k1, vitamin e acetate, vitamin a, palmitate, taurine, l-carnitine. ++a source of mfgm (milk fat globule membrane composed of proteins and fats) components ~a source of hmo (2'-fl & lnnt human milk oligosaccharides) #a source of arachidonic acid (ara) **a source of docosahexaenoic acid (dha)' '
Allergens & Warnings:
WARNING: Do not use a microwave oven to warm formula. Serious burns may result.Baby Formula Focus: Easy to Digest, Brain Development, Immune System Support
Base Ingredient: Milk
Dietary Needs: Kosher
Features: Added Prebiotics
Form: Powdered
State of Readiness: Mix
Package Quantity: 2
Age Stage: Infant
Net weight: 30 Ounces
Beverage container material: Paper or Cardboard
Street Date: October 20, 2017
TCIN: 52853961
UPC: 300875120415
Item Number (DPCI): 007-09-0123
Origin: Made in the USA or Imported
Grocery Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers. Any additional pictures are suggested servings only.
If the item details aren’t accurate or complete, we want to know about it.
Shipping details
Estimated ship dimensions: 9.8 inches length x 5.85 inches width x 3.89 inches height
Estimated ship weight: 2.09 pounds
Return details
This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup. If purchased online with SNAP EBT, this item must be returned within 90 days of the date it was shipped, delivered by a Shipt shopper, or made ready for pickup. This 90-day return window is required by SNAP.
See the return policy for complete information.
Q: Does the enfamil enspire refill how the measuring scoop
submitted by Monique W - 7 years ago
A: A scoop is included with our Enspire Refill Boxes. It is important to use a scoop from the same product you are using. During manufacturing, the scoop is placed in the container so that it's near the top when first opened. Sometimes, as the powder settles, the scoop settles down toward the bottom of the container. Please check to see if the scoop has settled to the bottom by cutting through the powder with a clean, dry utensil.
submitted byMike J - 6 years agoBrand expertA: How many bags are in the refill box
submitted byNy - 1 year agoA: Two bags of formula
submitted byRgran2 - 8 months agoA: Yes, there is one measuring scoop included.
submitted byKaitlin - 7 years ago
Q: Best way to transition to Similac version? Enfamil Enspire seems to always be out of stock and it has been removed from my stores instock inventory. Could I mix Enfamil Enspire and Similac 360 Total?
submitted by Alex - 3 years ago
A: Hello, Alex! We are so sorry to hear that. We started phasing out Enfamil Enspire in the fourth quarter of 2022. We started phasing out Enfamil Enspire when we launched Enfamil Enspire Optimum. We do not recommend alternating formulas back and forth due to the adjustment period that most babies go through when the formula is changed. If your baby’s doctor has recommended that you mix formulas, we suggest you discuss this with your doctor and follow his or her instructions. If your doctor has recommended another brand of formula for your baby, we usually suggest completely switching over to the new formula. Your baby's doctor is in the best position to guide you. -Katelin, Enfamil Expert
submitted byEnfamil Team - 3 years agoBrand expert
Q: what is the shelf life date of the product
submitted by Winnie - 8 years ago
A: It depends, I have seen the expire date be over a year away.
submitted byKaitlin - 7 years ago
Q: i am not quite sure what the refill box means.
submitted by zy - 8 years ago
A: This package does not include the plastic storage tub with the lid. Just two refill bags. You can purchase the formula powder in the reusable tub separately, and then buy the refills; or just store these bags in an airtight Tupperware container (that's what we do).
submitted byJT - 8 years ago
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Guests are saying
This formula is highly praised by guests for its close resemblance to breast milk, making it an excellent choice for supplementing or transitioning from breastfeeding. Many guests report that their babies love the taste and have experienced fewer digestive issues compared to other formulas. The inclusion of beneficial components like lactoferrin supports immune health, and its easy digestibility is a significant advantage for sensitive stomachs. Overall, it is a reliable option for parents seeking quality nutrition for their infants.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.8 out of 5 stars with 3692 reviews
easy on tummy: 4.81 out of 5
easy to prepare: 5 out of 5
quality: 4.9 out of 5
value: 4.55 out of 5
98% would recommend
72 recommendations
5 out of 5 stars
Thumbs up graphic, would recommend
3 January, 2026Verified purchase
One of the best out there!
It's hard picking over so many formulas out there. Especially when you're a first time mom and you want the best for your baby. After so much research I gave this one a try and I didn't have to keep searching! My baby loves it! I will definitely continue 5o use this for future babies. :)
5 out of 5 stars
20 December, 2025
originally posted on Enfamil
The only formula my breastfed baby would take.
[This review was collected as part of a promotion.] We tried a few different formulas that were labeled “close to breastmilk” but he wouldn’t take any until we tried Enfamil Optimum. Now I am able to have my baby take formula on the moments I may not be around.
1 reply from Customer Care team - 12 days ago
We work hard to bring you the very best products. Thanks for leaving us a review, Mommajx! — Tasha, Enfamil Expert
5 out of 5 stars
19 December, 2025
originally posted on Enfamil
Optimum is great my daughter loves it
I switched to this brand from great reviews I heard from family members. My daughter does not use any problems with it and the formula itself has a plethora of good vitamins and nutrients. It’s the perfect supplement for my child when not breast-feeding.
1 reply from Customer Care team - 15 days ago
We are so happy you chose us to supplement feedings for your little one, Courtland! Thank you for being part of our Enfamil family. — Tasha, Enfamil Expert
5 out of 5 stars
18 December, 2025
originally posted on Enfamil
I like it
[This review was collected as part of a promotion.] Just recently bought it to dual feed when i go back to work and my baby looks like there enjoying there bottles.Less spit up an less gassy.
1 reply from Enfamil Costumer Care team - 14 days ago
Hello Cherryberry! We would love to speak with you directly about your experience with our Enfamil Enspire pwd! One of our team members will be reaching out to you via email, but if you would like to speak with us immediately, please give us a call at 1-800-222-9123, select option 1 and reference #7708749. We look forward to speaking with you and seeing how we can help! -Hazel, Enfamil Expert
5 out of 5 stars
18 December, 2025
originally posted on Enfamil
Great choice
[This review was collected as part of a promotion.] Sometimes we get this one as a step up from the purple regular enfamil but a price cost below the purple optimum. I feel like the formula is softer and the powder is better and mixes well
1 reply from Enfamil Customer Care team - 13 days ago
Hello! We are glad to hear that you have been enjoying using our Enfamil® Optimum™! If you have any further questions, please give us a call at 1-800-222-9123, choose option 1, and reference #7708937. Thanks! - Enzo , Enfamil Expert
5 out of 5 stars
17 December, 2025
originally posted on Enfamil
ONE OF MY FAVORITES
[This review was collected as part of a promotion.] this formal is amazing switching between bf and formal feeding we have no spit up at all
1 reply from Customer Care team - 17 days ago
We work hard to bring you the very best products. Thanks for leaving us a review, Kadi! — Tasha, Enfamil Expert
5 out of 5 stars
15 December, 2025
originally posted on influenster.com
Gentle on the stomach, easy to mix, minimal spit-u
We’ve been using Enfamil Optimum Infant for our baby and it’s been working really well for us. One of the first things we noticed was how comfortable our baby seemed after feedings. Spit-up has been minimal compared to the formula we tried before, which was a big relief. We also haven’t had any issues with skin irritation or rashes, which was something we were watching closely. It seems gentle and easy on our baby’s stomach. The formula mixes smoothly and has a nice consistency — no clumps or foam — which makes bottle prep quick, especially during late-night feeds. Overall, our baby has been growing well and meeting developmental milestones, and we feel good knowing this formula supports brain development too. We’re happy with it and would definitely recommend it to other parents looking for a reliable, gentle formula.
1 reply from Enfamil Costumer Care team - 17 days ago
Hello! We would love to speak with you directly about your experience with our Enfamil® Optimum™ (Enspire)! One of our team members will be reaching out to you via email, but if you would like to speak with us immediately, please give us a call at 1-800-222-9123, select option 1 and reference #7686660. We look forward to speaking with you and seeing how we can help! -Hazel, Enfamil Expert
5 out of 5 stars
15 December, 2025
originally posted on Enfamil
this is really good for everyone has baby
[This review was collected as part of a promotion.] i got this for wonder box and i'm excited to used it
1 reply from Customer Care team - 18 days ago
What a great review, Chelsea! Thanks! — Marcy, Enfamil Expert
5 out of 5 stars
14 December, 2025
originally posted on Enfamil
Incredible formula!
I used this with both of my children. With my 9 month old currently and the purple one with my 6 year old back when it was still ENSPIRE. it worked very well with them and they both are sharp as a tack for their age and reached milestones earlier than the average baby. I think it has a lot to do with the ingredient found in breast milk which I’m so thankful for since I wasn’t able to breastfeed for very long
1 reply from Customer Care team - 18 days ago
We appreciate you using Enfamil with each of your babies and are happy that you continue to be a part of the Enfamil family! — Marcy, Enfamil Expert
5 out of 5 stars
12 December, 2025
originally posted on Enfamil
Closest thing to breast milk
[This review was collected as part of a promotion.] I used this in unison with breast feeding and my baby could hardly tell the difference. I had a hard time producing the amount of breast milk that I wanted to produce and wanted to make sure that my baby still got all the nutrients he deserved and this formula came in clutch.
1 reply from Customer Care team - 22 days ago
We work hard to bring you the very best products. Thanks for leaving us a review! — Tasha, Enfamil Expert
4 out of 5 stars
10 December, 2025
originally posted on Enfamil
Great source of nutrients
My baby has been using Enfamil formula since she turned 2 months and it has been great! No complications and she is big and healthy.
1 reply from Customer Care team - 23 days ago
We appreciate your feedback regarding our product, MelyN! Thank you for choosing Enfamil to help give your little girl the best start in life! — Tasha, Enfamil Expert
5 out of 5 stars
9 December, 2025
originally posted on Enfamil
Great milk
I bought this product few months ago and is super great
1 reply from Customer Care team - 24 days ago
What a great review, Daughter! Thanks! — Marcy, Enfamil Expert
5 out of 5 stars
9 December, 2025
originally posted on Enfamil
My favorite
This is my absolute favorite formula wish it wasn't so much but it's worth it
1 reply from Customer Care team - 24 days ago
Thank you for sharing your experience using our product, NLynn90! We appreciate your feedback! — Marcy, Enfamil Expert
5 out of 5 stars
9 December, 2025
originally posted on Enfamil
Great formula for supplementing
I bought this product for my daughter for supplementing due to my low milk supply. This formula has been so gentle on my daughter's stomach.
1 reply from Customer Care team - 24 days ago
We are so happy you chose us to help you supplement feedings for your little girl, MommaOf3! Thank you for being part of our Enfamil family. — Abby, Enfamil Expert
5 out of 5 stars
9 December, 2025
originally posted on Enfamil
No tummy issues
[This review was collected as part of a promotion.] We started my daughter (2mo) on this about a week after she was born. I breastfed/supplemented with donor milk while in the hospital. She has not had any digestive issues with this formula. Plenty of bowl movements and no serious gas.
1 reply from Enfamil Customer Care team - 25 days ago
Hello Kaitlin! We would love to speak with you directly about your experience with our Enfamil Enspire Optimum! One of our team members will be reaching out to you via email, but if you would like to speak with us immediately, please give us a call at 1-800-222-9123, select option 1 and reference #7653969. We look forward to speaking with you and seeing how we can help! - Jude, Enfamil Expert
5 out of 5 stars
8 December, 2025
originally posted on Enfamil
Love!
[This review was collected as part of a promotion.] Have never had any issues! Makes me feel good feeding it to my baby being close to breast milk.
1 reply from Customer Care team - 25 days ago
We appreciate your feedback regarding our product, Slp816! Thank you for choosing Enfamil to help give your little one the best start in life! — Tasha, Enfamil Expert
5 out of 5 stars
7 December, 2025
originally posted on Enfamil
Not yellow with an over powering smell
Love this for my past 3 babies and is going to be my choice for my 4th
1 reply from Customer Care team - 26 days ago
We appreciate you using Enfamil with each of your babies and are happy that you continue to be a part of the Enfamil family, Elizabeth! — Abby, Enfamil Expert
5 out of 5 stars
6 December, 2025
originally posted on Enfamil
Support immune system
[This review was collected as part of a promotion.] My bay started this fomula from second week. Easy to switch.
1 reply from Customer Care team - 26 days ago
Thank you for being part of the Enfamil family, Sonia. — Tasha, Enfamil Expert
5 out of 5 stars
6 December, 2025
originally posted on Enfamil
The best formula
This is the best formula to pick for your baby. It’s worth it!
1 reply from Customer Care team - 26 days ago
Thanks for such a great review, Sarah! — Tasha, Enfamil Expert
5 out of 5 stars
4 December, 2025
originally posted on Enfamil
Great Formula! Works well for my baby
[This review was collected as part of a promotion.] I bought this formula a couple of months ago when I had to start supplementing my breastfed baby. He was doing well on it. A couple weeks ago I made the decision to stop our breastfeeding journey due to low supply and he is loving Enfamil Optimum and doing very well on it. I highly recommend this to any mom looking for a formula to switch their breastfed baby to or any mom looking for formula!
1 reply from Customer Care team - 29 days ago
Thank you for telling us about your experience, lex1998. We are grateful for such a wonderful review! — Marcy, Enfamil Expert