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Tylenol Cold & Flu Severe Multi Symptom Caplets - Acetaminophen - 24ct - 2 of 4Tylenol Cold & Flu Severe Multi Symptom Caplets - Acetaminophen - 24ct - 3 of 4Tylenol Cold & Flu Severe Multi Symptom Caplets - Acetaminophen - 24ct - 4 of 4
Tylenol Cold & Flu Severe Multi Symptom Caplets - Acetaminophen - 24ct - 1 of 4

Tylenol Cold & Flu Severe Multi Symptom Caplets - Acetaminophen - 24ct

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At a glance

About this item

Highlights

  • Tylenol Cold + Flu Severe Pain Reliever & Fever Reducer Caplets for effective multi-symptom relief
  • Temporarily relieves fever, headache, minor aches and pains, sore throat, nasal congestion and cough
  • Also helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive
  • Each caplet contains 325 mg of acetaminophen to help reduce fever and relieve minor aches & pains
  • Each caplet contains 10 mg of the cough suppressant dextromethorphan HBr to help quiet coughs
  • Each caplet contains 5 mg of the nasal decongestant phenylephrine HCl to help relieve congestion
  • Each caplet contains 200 mg of the expectorant guaifenesin to help loosen phlegm (mucus)
  • From the #1 doctor-recommended pain relief brand, it is suitable for people 12 years and older

Description

Experience temporary relief from fever, sore throat, headache, nasal congestion, cough, and other cold and flu symptoms with Tylenol Cold + Flu Severe Caplets. This powerful pain reliever and fever reducer medicine tackles cold and flu symptoms by clearing congestion, quieting coughs, and relieving head and body aches. They also temporarily reduce fever and help loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive. Each caplet contains 325 milligrams of the pain reliever and fever reducer acetaminophen and 10 milligrams of the cough suppressant dextromethorphan HBr. Each pill also contains 200 milligrams of the expectorant guaifenesin and 5 milligrams of the nasal decongestant phenylephrine HCl. From the #1 doctor-recommended pain relief brand, this severe cold and flu medicine is suitable for adults and children 12 years and older for effective multi-symptom relief.
Trial/Mini/Travel Size: Yes
Suggested Age: 12 Years and Up
Health Facts: Contains Pain Reliever, Contains Acetaminophen
Active Ingredient Strength Value: 325 Milligrams
Product Form: Caplet
Primary Active Ingredient: Acetaminophen
Package Quantity: 24
Net weight: .04 Pounds
Features: Multi-Symptom, Daytime Use, Non-Drowsy
TCIN: 14013767
UPC: 300450270269
Item Number (DPCI): 094-14-0002
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

acetaminophen' '325.0mg dextromethorphan hbr' '10.0mg guaifenesin' '200.0mg phenylephrine hcl' '5.0mg

Purpose

Pain reliever/fever reducer Cough suppressant Expectorant

Uses

■ for the temporary relief of the following cold/flu symptoms: ■ minor aches and pains ■ headache ■ sore throat ■ nasal congestion ■ cough ■ helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive ■ temporarily reduces fever

Directions

Directions ■ do not take more than directed (see overdose warning) Adults and children 12 years and over ■ take 2 caplets every 4 hours ■ swallow whole; do not crush, chew or dissolve ■ do not take more than 10 caplets in 24 hours Children under 12 years: ask a doctor

Other information

©J&JCI 2020, Each caplet contains: sodium 3 mg

Inactive ingredients

inactive ingredients: carnauba wax, croscarmellose sodium, d&c yellow no. 10 aluminum lake, flavor, hydroxypropyl cellulose, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, pregelatinized starch, sucralose, titanium dioxide

Shipping details

Estimated ship dimensions: 0.94 inches length x 2.88 inches width x 4.55 inches height
Estimated ship weight: 0.07 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: Is it safe for breastfeeding mothers

submitted by Lizzy - 6 months ago

  • A: Thank you for inquiring about this and actually we normally advised breastfeeding mothers to contact the healthcare professional on using our products.

    submitted byKenvue - 6 months ago
    Brand expert

Q: What are the ACTIVE Ingredients and amounts in each caplet? The pictures of the product only Include inactive for some reason

submitted by MarciElle - 10 months ago

  • A: Hi please see the details below regarding the active ingredients. Acetaminophen 325 mg Dextromethorphan HBr 10 mg Guaifenesin 200 mg Phenylephrine HCl 5 mg

    submitted byKenvue - 10 months ago
    Brand expert

Q: Is this product halal or kosher?

submitted by Coat - 1 year ago

  • A: Hi, we don't have information if animal ingredients are present in these products since some of the ingredients are manufactured by the company. Others are purchased from outside distributors.

    submitted byKenvue - 11 months ago
    Brand expert

Q: Is this safe to use while pregnant?

submitted by Elizabeth - 2 years ago

  • A: Hi there! We'd recommend asking a healthcare professional before using Tylenol or any other over-the-counter medications.

    submitted byKenvue - 2 years ago
    Brand expert

Q: Will this help with chills?

submitted by College Student - 6 years ago

  • A: Hi there, so sorry for the delay! This product has a daytime product and a nighttime product. Daytime Uses for the temporary relief of the following cold/flu symptoms: minor aches and pains headache sore throat nasal congestion cough helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive temporarily reduces fever Nighttime Uses for the temporary relief of the following cold/flu symptoms: minor aches and pains headache sore throat nasal congestion cough sinus congestion and pressure sneezing and runny nose helps clear nasal passages relieves cough to help you sleep temporarily reduces fever

    submitted byKenvue - 5 years ago
    Brand expert

Q: is this non drowsy or the day version?

submitted by NY Chica - 8 years ago

  • A: Hi there! We wouldn't expect drowsiness while taking this product and it can be taken day or night. Feel free to reach out if there's anything else we can help with.

    submitted byKenvue - 7 years ago
    Brand expert

Q: is there any sulfa product in this

submitted by josh ridge - 8 years ago

  • A: Hey Josh! This product hasn't been tested for sulfa. We recommend reaching out to your doctor or pharmacist if you have any questions or concerns about this. We hope you have a great day!

    submitted byKenvue - 7 years ago
    Brand expert
See all questions (7)

Additional product information and recommendations

4.7 out of 5 stars with 978 reviews
quality: 4.46 out of 5
value: 4.42 out of 5
79% would recommend
29 recommendations
5 out of 5 stars
21 February, 2026
originally posted on influenster.com
Image

Very good

Fixes my headaches, it’s onset, the packaging is convenient, the dosage is very good it’s good making sure you only need the dosage to help your headache or pain
HaaniyaM
Did you find this review helpful?
5 out of 5 stars
17 February, 2026
originally posted on influenster.com
Image

👍🏽

This has to be one of the best cold meds you can take if you take it as soon as you start feeling any cold symptoms. I buy this every time and it works like a miracle!
KristinaC
Did you find this review helpful?
4 out of 5 stars
15 February, 2026
originally posted on influenster.com
Image

Okay for the most part

Works sometimes but worried about taking it for more than 24 hours. Don't think it's any better than store brands. It's a hit or miss for me. Once had a bad reaction to the pain reliever and stopped taking anything that has that ingredient.
MohamedM
Did you find this review helpful?
5 out of 5 stars
14 February, 2026
originally posted on influenster.com
Image

Relief the symptom

The best for any cold, congestion or fever. This is quick and the effects start as soon as like 5 minutes and last for 12 hours. The package is strong and bring enough pills for 6 months
NashalyB
Did you find this review helpful?
5 out of 5 stars
13 February, 2026
originally posted on influenster.com
Image

Best medication for pain

Best medication for headaches and pain. It works super fast, basically on the onset of symptoms. The instructions are super clear and the results last long. The storage location is simple and it’s over a great product. Good ingredients.
AgnaP
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
10 February, 2026

Finally, a "clean" formula that actually works!

As someone with a slower immune system, I am always looking for something that can actually help speed up the recovery process without adding unnecessary junk to my system. This is one of the few cold and flu medicines I have found that is made without Red 40, which I absolutely love. It helped me get back on my feet much faster than usual. Highly recommend for anyone who is mindful of dyes and needs reliable relief!
Adrian
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
5 out of 5 stars
9 February, 2026
originally posted on tylenol.com
Image

Everything that the box says it does believe it…

I buy 2 boxes at a time just to be on the safe side
Fay44
Did you find this review helpful?
5 out of 5 stars
6 February, 2026
originally posted on influenster.com
Image

Effective !

This is really good to take at night time this will make you drowsy but helps with serve cold symptoms. Works fast and is effective would deff recommend to a friend
JustinaF
Did you find this review helpful?
4 out of 5 stars
6 February, 2026
originally posted on influenster.com
Image

My first choice

When I get sick this is only medicine I’m running to the store to pick up. Love the simple packaging, and always takes alway the worse symptoms. That way I can continue on my day. I wish it was a bit more affordable but I love that it is easy to throw in my purse on the go.
Nicole N
Did you find this review helpful?
5 out of 5 stars
5 February, 2026
originally posted on influenster.com
Image

I recommend it

TYLENOL® Cold + Flu Severe Review TYLENOL® Cold + Flu Severe is very effective for relieving cold and flu symptoms. It helps reduce fever, headache, cough, and congestion quickly. I like that it provides fast relief and helps me feel more comfortable, especially at night. It’s easy to use and works well when symptoms are strong. I would recommend it for anyone needing reliable cold and flu relief.
Diana D
Did you find this review helpful?
5 out of 5 stars
26 January, 2026
originally posted on influenster.com
Image

Great deal

This is a great pill to take, for fast relief and it’s not hard on your tummy. Compact bottle size they also offer travel packets for travelers too. Great price
takeilam_8512
Did you find this review helpful?
5 out of 5 stars
24 January, 2026
originally posted on influenster.com
Image

Effective, easy and fast

It is very effective with getting rid of the pain. You can’t taste it, the dosages are clear on the bottle and accurate. The texture of the pill is smooth and it’s easy to swallow. I would recommend it.
oliviaw552_6582
1 guest found this review helpful. Did you?
5 out of 5 stars
23 January, 2026
originally posted on influenster.com
Image

Always my go to

This is always my go to when I am feeling a cold coming on. It’s easy to take on the go as each dose is individually packaged and can be broken off the pack.
laurenmelissa94_2978
Did you find this review helpful?
5 out of 5 stars
17 January, 2026
originally posted on influenster.com
Image

Helped with the super flu.

I used this for the flu this year and I will always be stocked in my cabinet. It works great it helped the most over everything I have tried. I was able to breathe and it really helped with the cough. Truly with getting.
wendyr357_559
1 guest found this review helpful. Did you?
5 out of 5 stars
7 January, 2026
originally posted on influenster.com
Image

Good brand and trusted

It’s the best when we are under the weather. Works fast and we trust the brand. The package is convenient and also safe for kids. Easy to store away and goo for travel.
anas1339_1291
Did you find this review helpful?
1 out of 5 stars
Thumbs down graphic, would not recommend
28 December, 2025

Didn't help

I purchased this in hopes that it would relieve my headache, body aches and other symptoms due to a cold. It hasn't helped at all!
Becca
quality: 1 out of 5
value: 1 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
26 December, 2025
originally posted on influenster.com
Image

Quick action without complications

It's very effective. I took it at work and it didn't make me drowsy, and I felt relief from my headache and mucus. I wanted to go home because I was at work, but luckily everything got better.
carolinag428_5664
Did you find this review helpful?
5 out of 5 stars
24 December, 2025
originally posted on influenster.com
Image

If you’re feeling sick this is the way

Everytime I get sick, this one helps me feel better. Every single time. I always carry them in my purse since I travel a lot for work and I usually get sick on planes/hotels and this is my to go stuff. Totally recommend it!
Allison P
Did you find this review helpful?
5 out of 5 stars
17 December, 2025
originally posted on influenster.com
Image

Fast relief for your worst cold days.

I grabbed these caplets during a rough cold, and they made a noticeable difference. My head felt clearer, and I could finally get some rest. Definitely keeping these on hand for when cold season hits!
caylah24_7419
Did you find this review helpful?
5 out of 5 stars
15 December, 2025
originally posted on influenster.com
Image

Quick onset and lasting relief!

My husband uses this product all the time! It lasts awhile and gives pain relief for at least 4-6 hours. It kicks in within about 30 ish minutes and the packaging makes it easy access. Overall a really great product!
abbym511_6521
Did you find this review helpful?

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