The Biochemistry of Inorganic Polyphosphates - 2nd Edition by Igor S Kulaev & Vladimir Vagabov & Tatiana Kulakovskaya (Hardcover)

Book Synopsis

Now in a second edition, Biochemistry of Inorganic Polyphosphates fills the need for an exhaustive resource on inorganic polyphosphate metabolism. The authors describe the structure and properties of these compounds and presents a comparative analysis of the newest and traditional methods of their extraction from cells. Distribution of polyphosphates in organisms, their localization in cells and tissues is also described.

• Comprehensive presentation of inorganic polyphosphate metabolism
• Follows polyphosphates in cells of organisms from different stages of evolution
• Presents methods for the analysis and study of polyP-dependent enzymes
• Comprehensive information on genetics, metabolism and biotechnology of polyphosphates
• Textbook and reference work on all aspects of polyphosphates

From the Back Cover

More than one hundred years ago, L. Liberman found high-polymeric inorganic polyphosphates (PolyP) in living organisms. These compounds are linear polymers containing a few to several hundred residues of orthophosphate (Pi) linked by energy-rich phosphoanhydride bonds. However, these mysterious cell components have as yet been ignored in most biochemistry manuals.

This research being undertaken in this fast-developing field often yields unexpected results revealing the most important regulatory mechanisms of the living cell.

The Biochemistry of Inorganic Polyphosphates 2nd edition concentrates on the modern concepts of PolyP biochemistry and includes such topics as

• the chemical structure and properties of condensed inorganic phosphates
• characteristics of the known enzymes of PolyP metabolism
• the functions of PolyP and PolyP-dependent enzymes, including phosphate and energy reservation, sequestration and storage of cations, formation of membrane channels, involvement in cell envelope formation and function, gene activity control, regulation of enzyme activities, participation in stress response and stationary phase adaptation.
• a critical analysis of the methods of isolation and quantitative assay of PolyP in the cells.
• localization and forms of PolyP in prokaryotic and eukaryotic cells
• the applied aspects of PolyP biochemistry.
• inorganic PolyP in chemical and biological evolution

This book will be of interest to research chemists, biochemists, microbiologists and postgraduate students.

Review Quotes

"This book is recommended for academic libraries supporting advanced biochemistry or related programs." (E-STREAMS, January 2005)

About the Author

Igor S. Kulaev is the author of The Biochemistry of Inorganic Polyphosphates, 2nd Edition, published by Wiley.

Vladimir Vagabov is the author of The Biochemistry of Inorganic Polyphosphates, 2nd Edition, published by Wiley.

Tatiana Kulakovskaya is the author of The Biochemistry of Inorganic Polyphosphates, 2nd Edition, published by Wiley.