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Sudafed PE Pressure + Pain Caplets - 24ct: Acetaminophen 325mg, Allergy and Sinus Treatment - 2 of 4Sudafed PE Pressure + Pain Caplets - 24ct: Acetaminophen 325mg, Allergy and Sinus Treatment - 3 of 4Sudafed PE Pressure + Pain Caplets - 24ct: Acetaminophen 325mg, Allergy and Sinus Treatment - 4 of 4
Sudafed PE Pressure + Pain Caplets - 24ct: Acetaminophen 325mg, Allergy and Sinus Treatment - 1 of 4

Sudafed PE Pressure + Pain Caplets - 24ct: Acetaminophen 325mg, Allergy and Sinus Treatment

$9.49 ($0.40/count)

In Stock

Eligible for registries and wish lists

At a glance

About this item

Highlights

  • Sudafed PE Sinus Pressure + Pain Relief Non-Drowsy Nasal Decongestant Tablets
  • Cold medicine with a non-drowsy formula relieves sinus pain, pressure, nasal congestion & headaches
  • Each tablet contains 5 mg of the decongestant phenylephrine HCl for nasal congestion relief
  • Each tablet contains 325 mg acetaminophen to relieve headache, minor pain & reduce fever
  • Tablets help relieve nasal congestion due to hay fever, common cold or upper respiratory allergies
  • Congestion medicine for relief of sinus pressure, headaches, nasal congestion, & minor aches & pains
  • This non-drowsy sinus congestion, pain & fever reducer medicine also helps promote sinus drainage
  • This product is HSA & FSA eligible. Check your plan for details as plans may vary.

Description

Get powerful relief of sinus congestion & pressure with pain, plus headaches with Sudafed PE Sinus Pressure + Pain Relief Maximum Strength Non-Drowsy Tablets. From the #1 pharmacist-recommended decongestant brand among oral OTC decongestants, the non-drowsy formula of this cold medicine contains 325 mg of acetaminophen, a pain reliever & fever reducer, & 5 mg of phenylephrine HCl, a nasal decongestant. This sinus pressure & pain medicine temporarily relieves nasal congestion & sinus symptoms associated with hay fever, upper respiratory allergies, & the common cold, such as sinus pressure, sinus headaches, & minor aches & pains. This decongestant medicine helps promote sinus drainage & temporarily reduces fever & relieves headaches. The maximum strength decongestant tablets can be used by adults & children 12 years & older for powerful sinus pressure, congestion & pain relief. Sudafed PE Sinus Pressure + Pain is HSA & FSA eligible. Check your plan for details as plans may vary.
Suggested Age: 12 Years and Up
Health Facts: Contains Pain Reliever
Active Ingredient Strength Value: 325 Milligrams
Product Form: Caplet
Primary Active Ingredient: Acetaminophen
Package Quantity: 24
Features: Non-Drowsy
TCIN: 14828170
UPC: 300450547248
Item Number (DPCI): 094-03-0131
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

acetaminophen' '325.0mg phenylephrine hcl' '5.0mg

Purpose

Pain reliever/fever reducer Nasal decongestant

Uses

■ temporarily relieves these symptoms associated with hay fever or other respiratory allergies, and the common cold: ■ sinus congestion and pressure ■ headache ■ minor aches and pains ■ nasal congestion ■ promotes sinus drainage ■ temporarily reduces fever

Directions

Directions ■ do not use more than directed (see overdose warning) Adults and children 12 years and over ■ take 2 tablets every 4 hours ■ do not take more than 10 tablets in 24 hours Children under 12 years: ask a doctor

Other information

Does not contain Pseudoephedrine, ©J&JCI 2018

Inactive ingredients

inactive ingredients: carnauba wax, fd&c yellow no. 6 aluminum lake, hypromellose, magnesium stearate, microcrystalline cellulose, modified starch, polyethylene glycol, polysorbate 80, powdered cellulose, pregelatinized starch, sodium starch glycolate, titanium dioxide

Shipping details

Estimated ship dimensions: 4.5 inches length x 2.9 inches width x 1 inches height
Estimated ship weight: 0.06 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: is this safe to take if you are on blood pressure medication?

submitted by Cricket - 6 years ago
  • A: My pharmacist told me no more of my favorite little pill when I was prescribed blood pressure meds. This was the best for me!

    submitted byLegalbird - 5 years ago
  • A: Hey Cricket! We recommend speaking with your doctor or pharmacist before taking this product while on blood pressure medication. We hope you have a great day!

    submitted byKenvue - 6 years ago
    Brand expert

Q: Is this safe for pregnancy?

submitted by User1 - 2 years ago
  • A: Hi, it's best to consult a healthcare professional before using the product. For more information, please visit https://www.sudafed.com/.Thank.

    submitted byKenvue - 2 years ago
    Brand expert

Additional product information and recommendations

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Guests are saying

This product has garnered a strong reputation among guests for its effectiveness in relieving sinus pressure, headaches, and congestion. Many guests appreciate its fast-acting formula, which provides relief from symptoms associated with sinus infections and allergies. While some guests experienced side effects or found it less effective, the majority highlight its ability to alleviate discomfort quickly, making it a go-to choice for sinus-related issues.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.5 out of 5 stars with 577 reviews
    effectiveness: 3.74 out of 5
    quality: 3.74 out of 5
    value: 3.67 out of 5
    70% would recommend
    34 recommendations
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    12 April, 2026

    (no review title)

    Ok it cleared up my sinuses BUT I will warn it makes you loopy and makes your heart palpitate. I think it should it state that
    Amee
    3 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    24 February, 2026Verified purchase

    Takes the pressure pain away!!!

    I had bad congestion to the point where my head was hurting so bad for days and it caused pain in my tooth from the sinus pressure I had. As soon as I took these the pain went away that same day and never came back. It was 100% worth it. If you’re sick and suffering from bad congestion you need to try these out.
    Kay
    effectiveness: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    3 guests found this review helpful. Did you?
    4 out of 5 stars
    2 February, 2026
    originally posted on influenster.com
    Image

    Works for me

    I take this when I get a cold since it doesn't make me drowsy and I stay alert. It works great for me when I take it when having early symptoms. The price is cheaper than some other brands.
    timothyv18
    Did you find this review helpful?
    3 out of 5 stars
    30 December, 2025
    originally posted on influenster.com
    Image

    Little bit pricey!

    It works to get rid of a sinus headache! They are pretty big pills though so if you have hard time swallowing pills it may make it more difficult to swallow.
    allies240
    Did you find this review helpful?
    5 out of 5 stars
    18 December, 2025
    originally posted on influenster.com
    Image

    Sudafed is a go to when sick.

    This product is extremely helpful when I'm sick. It is easy to swallow. It helps relieve the sinus pressure and makes my congestion better. It helps to feel better in general.
    rachell751
    Did you find this review helpful?
    1 out of 5 stars
    14 December, 2025

    (no review title)

    Did not get this item. Looks like they forgot it
    Marsha
    Did you find this review helpful?
    4 out of 5 stars
    12 December, 2025
    originally posted on influenster.com
    Image

    Good

    I suffer from regular sinus issues, while this does not completely get rid of my symptoms. It helps a lot and I get some relief from my symptoms. So would recommend.
    shannonk294
    Did you find this review helpful?
    5 out of 5 stars
    4 December, 2025
    originally posted on influenster.com
    Image

    Number one go to

    Sudafed is literally the best medicine for sinuses. It cleared my sinuses within 30 minutes and I can finally breathe. It is an amazing product and it is the only medication I'll take when I have sinus flareups.
    malih2
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    23 November, 2025Verified purchase

    Awesome

    Very effective! Works great
    Mango
    effectiveness: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    4 out of 5 stars
    16 November, 2025
    originally posted on influenster.com
    Image

    Great product, works well

    I tried these the last time I had a bad sinus headache and they worked pretty well. They helped relieve most of the pain and pressure that I was feeling, thus helping me to get back to normal life quicker. The pills are easy to swallow.
    mommato6kids
    Did you find this review helpful?
    5 out of 5 stars
    25 October, 2025
    originally posted on influenster.com
    Image

    Take 2 sinus champ!

    The Take 2 champ for sinus relief. A bit pricey but totally worth it. Your head and sinus pressure definitely relieved in minutes. Every time I feel even a bit of sinus pressure especially in Florida boom pop two and feel good.
    klove92
    Did you find this review helpful?
    5 out of 5 stars
    21 October, 2025
    originally posted on influenster.com
    Image

    Effective product

    I take Sudafed pretty regularly its the only thing that helps me and my husband. Its super effective and a great price for the product plus you can get it anywhere.
    viktoriaf22
    Did you find this review helpful?
    5 out of 5 stars
    19 October, 2025
    originally posted on influenster.com
    Image

    Family first

    This was easy to open at home. I felt better within the hour of taking it. I always have this in stock for my family. You never know when allergies will turn into more.
    cassieg117
    Did you find this review helpful?
    5 out of 5 stars
    19 October, 2025
    originally posted on influenster.com
    Image

    Fast relief for sinus pressure, pain, and congestion.

    Sudafed PE Pressure + Pain provides powerful relief from sinus pressure, headaches, and congestion. Its effective formula combines a pain reliever and decongestant to quickly clear nasal passages and ease discomfort. Easy to swallow and fast-acting, it helps you feel normal again without feeling drowsy. A trusted solution for cold and allergy relief when sinus pressure hits hard.
    phungn11
    Did you find this review helpful?
    5 out of 5 stars
    16 October, 2025
    originally posted on influenster.com
    Image

    My sinus go to!

    This is my go to for when sinus and allergy season goes into effect, it's literally the only thing that helps. The offer several different quantities which also helps. Definitely recommend this for the sinus pressure.
    meganr703
    Did you find this review helpful?
    5 out of 5 stars
    14 October, 2025
    originally posted on influenster.com
    Image

    Fast acting and powerful

    This product has saved my life multiple times through flu or allergies. It is extremely effective and fast acting, clearing up symptoms of sinus congestion and pain. Definitely recommend!
    adriai1
    Did you find this review helpful?
    5 out of 5 stars
    24 July, 2025
    originally posted on influenster.com
    Image

    may make you drowsy

    i was down bad for a week before finding this gem! i definitely felt better within 2 days of taking it, my symptoms drastically improved and i was able to go back to work a day early
    shifaa16
    Did you find this review helpful?
    5 out of 5 stars
    21 July, 2025
    originally posted on sudafed.com
    Image

    The only thing that works

    Works like a charm when I have sinus pressure the whole family uses this product. It is very effective for relieving pressure.
    Sandy
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    20 April, 2025Verified purchase

    Sudafed PE

    Definitely my go to sinus pressure medicine. Switch this and Claritin out often.
    kbrook
    effectiveness: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    2 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    7 March, 2025

    Not the same

    I've used this for years, it was always my go to when I'd feel a sinus infection coming on. But this last time I bought it expecting the same great relief..nothing. It was as if I didn't take anything at all. The pressure n pain was still there, did they switch up the formula? Like everything else that worked well long ago doesnt anymore and sadly this is one of them products.
    TargetLady
    effectiveness: 1 out of 5
    quality: 1 out of 5
    value: 1 out of 5
    5 guests found this review helpful. Did you?

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