Nitrenes and Nitrenium Ions - (Wiley Reactive Intermediates in Chemistry and Biology) by Daniel E Falvey & Anna D Gudmundsdottir (Hardcover)

About the Book

"Nitrenes and Nitrenium ions are reactive intermediates with monovalent nitrogen atoms. These intermediates have diverse reactivity and physical properties, depending on their structure and spin state. The leading experts in nitrene chemistry have contributed to this book to highlight how spectroscopy and calculations have been used to characterize various nitrene intermediates. Emphasizes have also been placed on identifying the diverse methods to form these intermediates. Furthermore, the reactivity of nitrenes and nitrenium ions is discussed in details and how the reactivity can be used in various applications"--

Book Synopsis

Featuring contributions respected leaders in the field, Nitrene and Nitrenium Ions is the first comprehensive book to explore the role of reactive intermediate nitrene and nitrenium ions in chemistry and biochemistry. Covering a broad range of topics, including ultrafast studies, computational studies, behavior in aqueous solution, electronic structures, and reactions with aromatic compounds, this valuable resource will empower graduate students and researchers to better understand and expand their synthetic utility.

From the Back Cover

Presents advanced experimental and theoretical methods to characterize nitrenes and nitrenium ions

Nitrenes and nitrenium ions are reactive intermediates with monovalent nitrogen atoms. These intermediates have diverse reactive and physical properties, depending on their structure and spin state. With contributions from leading international experts in nitrene chemistry, this book describes the most advanced computational, spectroscopic, and chemical methods for characterizing and working with these important reactive intermediates. Throughout the book, the authors identify a broad range of tested and proven methods to form nitrenes and nitrenium ions. Moreover, they explain how to take full advantage of their reactive properties to support a variety of applications.

Nitrenes and Nitrenium Ions begins with a brief overview and then explores current and emerging topics in the field such as:

• Exciting new findings stemming from advanced femtosecond and time-resolved vibrational spectroscopy studies that reveal unexpected complexities in the behavior of arylnitrene and nitrenium ions
• Dynamics and properties of nitrenes and nitrenium ions discovered using contemporary computational methods
• Behavior of nitrenes and nitrenium ions in biochemical and synthetic reactions
• Nitrenes and nitrenium ions with unusual structures or physical properties
• Role of nitrenes and nitrenium ions in biochemical processes that damage DNA

Each chapter, dedicated to a specific research topic, ends with references that provide a gateway to the original research studies and reviews in the field.

Nitrenes and Nitrenium Ions is recommended for students and researchers who want to improve their understanding of these important reactive intermediates and take full advantage of them in order to develop a variety of fine chemicals and pharmaceuticals.

About the Author

DANIEL E. FALVEY, PhD, is Professor at the University of Maryland. His research focuses on reaction mechanisms and reactive intermediates, with an emphasis on the exploration of intermediates that play a role in biochemical processes. Dr. Falvey has been awarded the Merck Award and the Reynold C. Fuson Memorial Award in Chemistry. Acclaimed for his teaching abilities, he has received the Outstanding Teacher Award from the Center for Teaching Excellence.

ANNA D. GUDMUNDSDOTTIR, PhD, is Professor of Chemistry at the University of Cincinnati. Dr. Gudmundsdottir's studies photo-removeable protecting groups, reactive intermediates, and polymer modification. Her research team elucidated the reactivity of triplet alkyl and vinyl nitrenes in solution and solid state using transient spectroscopy and matrix isolation. Among her many honors, Dr. Gudmundsdottir is a recipient of the NSF CAREER Award.