Neurofibromatosis Type 1 in Childhood - (International Review of Child Neurology (Mac Keith Press)) by Kathryn North (Hardcover)

About the Book

A thoughtful and clinically valuable account which will aid both treatment of and research into this difficult disorder.

Book Synopsis

A great deal is now known about neurofibromatosis type 1, particularly as a result of the identification of its causative gene by positional cloning. However, effective treatments for its resulting cosmetic disfigurement, impaired cognitive performance and even life-threatening malignancy remain elusive. As Dr. Korf remarks in his Foreword: "this book's cogent and thorough description of neurofibromatosis in children will take its place alongside other major clinical studies of the disorder. [Dr. North] has tackled some of the more challenging issues, such as the basis for learning disabilities and the optimal means for early detection of optic gliomas. Her work provides a guide to the clinician and stands as a provocative challenge to the neurofibromatosis research community to further explore the basis of these problems."

From the Back Cover

A great deal is now known about neurofibromatosis type 1, particularly as a result of the identification of its causative gene by positional cloning. Effective treatments for its resulting cosmetic disfigurement, impaired cognitive performance and even life-threatening malignancy however sadly remain elusive.

As Dr Korf remarks in his Foreword; 'this book's cogent and thorough description of neurofibromatosis in children will take its place alongside other major clinical studies of the disorder. (Dr North) has tackled some of the more challenging issues, such as the basis for learning disabilities and the optimal means for early detection of optic gliomas. Her work provides a guide to the clinician and stands as a provocative challenge to the neurofibromatosis research community to further explore the basis of these problems.'

• Unique account of the basis of learning disorder in this condition


• Provides guidance on optimal methods for early detection of optic glioma


• A thorough review of current knowledge of neurofibromatosis in childhood

Review Quotes

"...North provides an excellent review of this multisystem disorder and includes the most recent developments in the field...Overall, this book is well written and easy to read. The style makes it easy to assimilate...This book is relevant to all neurologists but most particularly to the pediatric neurologist. I would also recommend this volume to health care personnel involved in neurofibromatosis clinics." Archives of Neurology

About the Author

Kathryn North, New Children's Hospital, Parramatta, Australia

Foreword by Bruce R. Korf
With contributions by David Gutman
Preface by Peter G. Procopis