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Excedrin Migraine Pain Reliever Caplets - Acetaminophen/Aspirin (NSAID)
$12.99 ($0.13/count)
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About this item
Highlights
- One bottle of 100 Excedrin Migraine Caplets for Migraine Headache Relief
- Excedrin Migraine works in 3 ways to relieve migraines fast
- Provides migraine relief, including migraine headache pain, sensitivity to light and sound, nausea
- With acetaminophen and aspirin as pain relievers, and caffeine to enhance their analgesic effect
- Delivers a powerful triple action formula with two pain relievers and an amplifier
- HSA and FSA eligible product
Description
Excedrin Migraine Caplets for Migraine Headache Relief provide migraine relief fast, making Excedrin Migraine the #1 neurologist recommended OTC treatment for migraines.* Excedrin works in 3 ways to relieve migraines: it blocks pain signals, elevates your pain threshold and uses caffeine to enhance the pain relief effect. Available in convenient caplet form, this powerful migraine medicine delivers a specialized triple action formula containing two pain relievers and an amplifier. These Excedrin caplets combine aspirin and acetaminophen with caffeine to provide migraine relief, including migraine headache pain, sensitivity to light and sound, and nausea. For some, this migraine headache medicine starts relieving migraine pain in 30 minutes. Get migraine relief fast with Excedrin, the headache expert.
*Among OTC medicine for migraines IQVIA, Inc., 2018
*Among OTC medicine for migraines IQVIA, Inc., 2018
Suggested Age: 12 Years and Up
Health Facts: Contains Aspirin, Contains Acetaminophen
Active Ingredient Strength Value: 250 Milligrams
Product Warning: Keep out of reach of children
Product Form: Caplet
Primary Active Ingredient: Acetaminophen
Package Quantity: 100
Net weight: 3.46 Ounces
TCIN: 11009981
UPC: 300672039835
Item Number (DPCI): 094-01-0235
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
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Active ingredients
acetaminophen(250mg), aspirin (nsaid)(250mg), caffeine(65mg).
Purpose
Pain Reliever, Pain Reliever, Pain Reliever Aid..Allergy alert: Aspirin may cause a severe allergic skin reaction which may include:
Allergy alert: Aspirin may cause a severe allergic skin reaction which may include:: hives,facial swelling,asthma (wheezing),shock.Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take
Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 2 caplets in 24 hours, which is the maximum daily amount,with other drugs containing acetaminophen,3 or more alcoholic drinks every day while using this product.Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you
Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you: are age 60 or older,have had stomach ulcers or bleeding problems,take a blood thinning (anticoagulant) or steroid drug,take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others),have 3 or more alcoholic drinks every day while using this product,take more of for a longer time than directed.Do not use
Do not use: if you have ever had an allergic reaction to acetaminophen, aspirin or any other pain reliever/fever reducer,with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.Ask a doctor before use if
Ask a doctor before use if: you have never had migraines diagnosed by a health professional,you have a headache that is different from your usual migraines,you have the worst headache of your life,you have fever and stiff neck,you have headaches beginning after or caused by head injury, exertion, coughing or bending,you experienced your first headache after the age of 50,you have daily headaches,you have a migraine so severe as to require bed rest,you have liver disease,stomach bleeding warning applies to you,you have a history of stomach problems, such as heartburn,you have high blood pressure, heart disease, liver cirrhosis, or kidney disease,you are taking a diuretic,you have asthma,you have problems or serious side effects from taking pain relievers or fever reducers,you have vomiting with your migraine headache.Ask a doctor or pharmacist before use if you are
Ask a doctor or pharmacist before use if you are: taking a prescription drug for: diabetes; gout; arthritis,under a doctor's care for any serious condition,taking any other drug,taking any other product that contains aspirin, acetaminophen, or any other pain reliever/fever reducer.Stop use and ask a doctor if
Stop use and ask a doctor if: an allergic reaction occurs. Seek medical help right away,you experience any of the following signs of stomach bleeding: feel faint; vomit blood; have bloody or black stools; have stomach pain that does not get better,you migraine is not relieved or worsens after first dose,new or unexpected symptoms occur,ringing in the ears or loss of hearing occurs.Directions
Do not use more than directed.Adults
Take 2 caplets with a glass of water. If symptoms persist or worsen, ask your doctor. Do not take more than 2 caplets in 24 hours, unless directed by a doctor.Under 18 Years of Age
Ask a doctor.Other information
Store at controlled room temperature 20 degrees - 25 degrees C (68 degrees - 77 degrees F). Close cap tightly after use. Read all product information before using. Keep this box for important information.Inactive ingredients
benzoic acid, carnauba wax, fd&c blue no. 1, hypromellose, light mineral oil, low-substituted hydroxypropyl cellulose, microcrystalline cellulose, polysorbate 20, povidone, propylene glycol, simethicone, sorbitan monolaurate, stearic acid, titanium dioxide
Question or comments?
800-468-7746Shipping details
Estimated ship dimensions: 6.25 inches length x 4.37 inches width x 2.32 inches height
Estimated ship weight: 0.67 pounds
Return details
This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.
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Guests are saying
Excedrin Migraine is a highly effective over-the-counter medication that combines acetaminophen, aspirin, and caffeine to provide quick relief from migraines. Many guests appreciate its fast-acting formula, often reporting significant pain reduction within 30 minutes. The compact packaging makes it convenient for on-the-go use, and its affordability adds to its appeal. While some guests note potential stomach sensitivity, the overall consensus is that it is a reliable choice for managing migraine symptoms.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.8 out of 5 stars with 5596 reviews
quality: 4.71 out of 5
value: 4.6 out of 5
97% would recommend
36 recommendations
5 out of 5 stars
21 December, 2025
originally posted on influenster.com

Great product
[This review was collected as part of a promotion.] Works great and pretty fast as well, easily portable. Ok size pills, texturally average. Great value for how consistent they do the job well. Very satisfied
5 out of 5 stars
20 December, 2025
originally posted on influenster.com

Excelent option
[This review was collected as part of a promotion.] Great mediccine, have a nice bottle and fast efect. You Can have it at your purse and dont have Any problem. 100 pillls are good vs price and effective.
5 out of 5 stars
19 December, 2025
originally posted on influenster.com

Love
[This review was collected as part of a promotion.] This is my go to migraine relief when I’m having a breakthrough migraine or during the times that I have been medicated for my migraines. It’s available everywhere and works pretty quickly!
5 out of 5 stars
18 December, 2025
originally posted on influenster.com

Migraine
[This review was collected as part of a promotion.] I take this when I feel a migraine coming on and it works very quickly and helps relieve all migraine symptoms. Reliable when you need fast relief
5 out of 5 stars
18 December, 2025
originally posted on influenster.com

Might be your key to OTC migraine relief
[This review was collected as part of a promotion.] Migraine pain is different, but you can still reach for a familiar brand to treat it. *I'm not a doctor, just a person offering a personal review of a complimentary product.* Excedrin Migraine Relief Caplets provide a different pain-fighting formula in a name you can trust. Excedrin Migraine combines acetaminophen and aspirin for pain relief and amplifies the effects with caffeine in convenient caplet form. This formula works in three ways to relieve migraines: blocking pain signals, elevating the pain threshold, and enhancing the pain relief effect while relieving sensitivity to light and sound, and combating nausea. For my level of migraine pain, this product didn't quite take care of it, unfortunately. However, I already use a prescription level product for migraines under physicians’ care. If you're looking for an OTC complement or treatment for migraine symptoms, Excedrin Migraine Relief Caplets might be what you need. Best wishes to you to feel better.
5 out of 5 stars
18 December, 2025
originally posted on influenster.com

Is a lifesaver for migraines
[This review was collected as part of a promotion.] This is a review of 'Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms - 200 Count.' They keep me alive. No kidding. I live on Excedrin. They are probably my primary food group. I get migraine headaches, and, for whatever reason, the combination of ingredients in Excedrin not only helps manage my pain, but usually eliminates it. If I take the ingredients separately (aspirin + acetaminophen + caffeine), it does little for my pain; if I take the same ingredients in 2 Excedrin, the pain is gone. Wow!
5 out of 5 stars
18 December, 2025
originally posted on influenster.com

Reliable relief recommended for early symptoms to
[This review was collected as part of a promotion.] Excedrin Migraine has been one of the more reliable options for me when a migraine starts coming on that I’ve kept on hand for 20 years. It works best if I take it early—usually within 30–45 minutes I notice a real decrease in pain. That said, it’s not perfect. If I take it on an empty stomach, it can make me feel a bit jittery or nauseous, likely because of the caffeine. It also doesn’t fully knock out more severe migraines, but it often brings the pain down to a manageable level where I can function, which is the goal for me. Overall, it’s something I keep on hand for moderate migraines or early symptoms. Not a cure-all, but dependable enough that I reach for it when I first get an aura before stronger options.
5 out of 5 stars
17 December, 2025
originally posted on influenster.com

Works
[This review was collected as part of a promotion.] Works like wonders! I never had a pill that works almost instantly. Packaging is good to fit in your purse for on the go. Storage holds enough pills in it . I do recommend this to my coworkers . Dosage is a good amount
5 out of 5 stars
17 December, 2025
originally posted on influenster.com

A must have in the medicine cabinet
[This review was collected as part of a promotion.] Recently I had the worst migraine I mean lights sounds anything was triggering I had to sit in my bathroom in the dark and try not to move for about 30 min then remembered this I took it and 20 min later I could stand and slowly start going I took low lit rooms. It was a life saver.
5 out of 5 stars
16 December, 2025
originally posted on influenster.com

Perfect formula to always get the job done!
[This review was collected as part of a promotion.] Not gonna lie, not my first time using Excedrin, but when someone offers you a free product you already know and like it’s hard to say no. I have never experienced faster relief with other migraine medications and there is a reason for the heavy duty ones I don’t mess around I just skip straight to it. It works and works freaking well!
5 out of 5 stars
16 December, 2025
originally posted on influenster.com

Great for lighter migraine days!
[This review was collected as part of a promotion.] Excretion migraine works great for those lighter migraine days when I don’t want to take something as strong as my prescription. The caffeine helps in addition to the two types of pain relievers.
5 out of 5 stars
15 December, 2025
originally posted on influenster.com

Excedrin Migraine Relief is fast, effective, and d
[This review was collected as part of a promotion.] Effective for winters flares. Fast migraine relief in ~30 min, lasts hours. I take 2 as directed, no tolerance issues. Easy storage, reliable.
5 out of 5 stars
14 December, 2025
originally posted on influenster.com

Effective fast relief
[This review was collected as part of a promotion.] I received these from influencer from my honest review. I do get migraines a lot and have to take prescription medicine. It can get Expensive at times. One thing I noticed about the Excedrin for headaches is it also took care of my aches and pains that are associated with my migraines . I definitely will be buying more of these because it is convenient to be able to go to a drugstore and just grab a regular product off the shelf
5 out of 5 stars
13 December, 2025
originally posted on influenster.com

Easy administration
[This review was collected as part of a promotion.] This product is invaluable. When you feel bad with your migraine, it helps with the symptoms. Any additional reactions, any smell, great consistency, easy administration, any further response, duration relieves.
3 out of 5 stars
13 December, 2025
originally posted on influenster.com

Great backup
[This review was collected as part of a promotion.] I have migraines and a specific prescription but if I am out and don’t have any, this stuff definitely helps ease the pressure until I can get home to take a pill. I’m super grateful for slight relief from the awful pain!
4 out of 5 stars
12 December, 2025
originally posted on influenster.com

Good product.
[This review was collected as part of a promotion.] I definitely take these when I’m at work and during a long day. I’ve been dealing with migraines a lot lately and this helps with the pain. I do have to be careful though since it has caffeine in it and I’m more on the holistic side of dealing with headaches, but this is a good alternative when I’m really needing something a little stronger.
5 out of 5 stars
12 December, 2025
originally posted on influenster.com

Works great when you cant use your prescription
[This review was collected as part of a promotion.] I like having this on hand for when I'm busy or have stuff to get done when a migraine hits. My prescriptions sometimes knock me out or make my head feel foggy, but this helps keep me going and actually helps ease the pain.
5 out of 5 stars
12 December, 2025
originally posted on influenster.com

Little Miracles
[This review was collected as part of a promotion.] These have been a life savor for me lately ! I drink and take quite a bit of caffeine and I am a highly stressed out person which brings on migraines frequently. I am able to take 2 of these and pair it with plenty of water and my headache usually goes away within an hour . I’m so happy because headaches/migraines are incredibly miserable . These make it so I can function
5 out of 5 stars
11 December, 2025
originally posted on influenster.com

EXCEDRIN that’s girl
[This review was collected as part of a promotion.] Excedrin is nothing new to me. I’ve definitely used this in my time of need and it definitely does help. It has always been a staple in my household and will continue in the future. it does what it needs to do and it does have the instructions on it if you need help.
5 out of 5 stars
11 December, 2025
originally posted on influenster.com

Fast acting!
[This review was collected as part of a promotion.] The only thing that helps my migraines! Fast acting relief. The packagingbis great that so many pills come in the package and it is easy to open and store!