Advances in Drug Discovery Techniques - by Alan L Harvey (Hardcover)

About the Book

A guide to techniques for the discovery and evaluation of pharamcologically active compounds for therapeutic development, this book covers rational drug design, high-throughput screening, and genetic approaches to drug discovery. The authors focus on advances in the use of combinatorial chemistry and natural products, both of which support the chemical diversity for many drug screening programmes. They examine typical screening studies and their link to robotics and informatics in detail and present an overview of current progress within anitsense therapeutics. The book explores the rapid changes in drug discovery resulting from developments in molecular biology, robotics, and informatics.

Book Synopsis

Pharmazieunternehmen verwenden zwar immer mehr Mittel, Zeit und Personal auf Forschung und Entwicklung, jedoch sinkt die Zahl der jährlich neu zugelassenen Medikamente weiter ab. Dieses Buch zeigt Wege auf, die zu neuen Wirkstoffgruppen führen können, wobei die Betonung hier eher auf einem breiten Überblick, als auf einer detaillierten Besprechung einzelner Methoden liegt. Ausführlich analysiert werden die Veränderungen, die sich gegenwärtig in der pharmazeutischen Forschung und Entwicklung manifestieren. (06/98)

From the Back Cover

This invaluable volume serves as a guide to up-to-the-minute techniques for the discovery and evaluation of pharmacologically active compounds for therapeutic development. Focusing on practical applications, provided by expert practitioners from both industry and academic research laboratories, Advances in Drug Discovery Techniques covers rational drug design, high-throughput screening and genetic approaches to drug discovery. Moreover, chapters also focus on advances in the use of combinatorial chemistry and natural products, both of which support the chemical diversity for many drug screening programmes. Typical screening studies and their link to robotics and informatics are also presented in detail, together with an overview of current progress within antisense therapeutics. Overall, this book will be an excellent reference source for all individuals interested in making sense of the rapid changes in drug discovery that result from developments in molecular biology, robotics and informatics.

About the Author

Alan L. Harvey is the author of Advances in Drug Discovery Techniques, published by Wiley.